Spontaneous Remission of Type 1 Diabetes

Insulin Remissions among Pregnant Type 1 Patients

The fact that has been known for many decades but rarely mentioned is that when women with Type 1 diabetes become pregnant, their condition improves, and some become insulin-free during pregnancy. But pregnancy doesn't cure type 1 diabetes because, after delivery, they again become affected with type 1 diabetes

Note! Insulin Remissions among Pregnant Type 1 Patients have recently been highlighted by Dr Louis Jovanovic at the International Summit on Insulin Independence - on April 24, 2013

Quote:

One-third of pregnant women, including those who’ve had it for 20 years or more, have reduced insulin needs during pregnancy

Among pregnant type 1 women, there is often a decline in the need for insulin

Some women have been insulin-free throughout their pregnancy, only to return to insulin requirements after delivery.

New insulin production has been seen among type 1 patients with a history of diabetes for more than 20 years

*Jovanovic L, et all.,Diabetologia. 2000 Oct;43(10):1329-30.

Source: International Summit on Insulin Independence - April 24, 2013, http://insulinindependence.com/insulin-independence-program.html

1. The fact that a “Third of pregnant women, including those who’ve had it for 20 years or more, have reduced insulin needs during pregnancy” should be regarded as a partial remission of Type 1 Diabetes.

2. The fact that “Some women are insulin-free throughout their pregnancy – can be regarded as a temporary cure for Type 1 diabetes.

3. The fact that women “return to insulin requirements after delivery” – can be regarded as the reoccurrence of Type 1 diabetes.

The question is do women return to insulin requirements immediately after delivery, or after a few days, weeks or even months? At this moment, I can only guess until more data is available. However, it is hard to assume that they return on insulin requirements immediately after delivery. It is more likely that they return after a period of delivery. Also, it is hard to assume that there is a fixed timeline. It is very likely that some women return to insulin requirements in a shorter time, and some take a while longer after delivery.

The example of partial remission and temporary cure of Type 1 diabetes during pregnancy points out that; the musculoskeletal and biomechanical changes during pregnancy are responsible for the partial remission and cure of type 1 diabetes. The return of the pre-pregnancy biomechanics – (posture and gait) and the pre-pregnancy shape of the musculoskeletal system causes Type 1 diabetes.

The example that islet cells regenerate during pregnancy further strengthens the conclusion that biomechanical and musculoskeletal changes are the reasons for the regeneration of islet cells.

Quote: By 10 weeks of pregnancy, new endogenous levels of insulin are seen. Johansson M at al. Endocrinology 2006. 147(5):2315 – 232

The fact that new insulin production starts after 10 weeks of pregnancy suggests that at that time, the regeneration of islet cells starts. New endogenous levels of insulin aren’t seen in the first or second week of pregnancy because there are almost no musculoskeletal changes. Musculoskeletal changes are visible around 10 weeks of pregnancy.

Please note: All women during pregnancy are affected by anatomical and physiological changes. But some of them are more and some of them are less affected by musculoskeletal changes during pregnancy.

Side note: For now, there is only one example (Halle Berry) where Type 1 diabetes is cured by pregnancy. (Actually, musculoskeletal changes and the change in the biomechanics during pregnancy is the reason for the cure of Type 1 diabetes.) The question is, how many other women have become permanently insulin-free or have permanently reduced their dependence on insulin injection after delivery. It is very likely that due to the accepted views such as; Type 1 diabetes is an autoimmune disease; diabetes type 1 cannot be cured, etc., those cases are ignored by the established scientific-pharmaceuticals community.

The Size of the Pancreas of People with Type 1 Diabetes

One crucial fact about Type 1 diabetes, which is rarely mentioned, is the fact that the size of the pancreas of people with type 1 diabetes is significantly smaller than that of people without Type 1 diabetes.