Modern Science of Biomechanics and Type 1 Diabetes


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Spontaneous Remission of Type 1 Diabetes

The examples of (spontaneous) islet cells regeneration leads to the suggestion that Type 1 diabetes is possible to cure.

Quote:

Only in rare instances do islets regenerate.  These times include acute pancreatic injury, pancreatitis, pancreatic stones and pregnancy.

 Johansson M at al. Endocrinology 2006. 147(5):2315 – 232

The example that acute pancreatic injury, pancreatitis and pancreatic stones cause (indirectly) a regeneration of islets cells points out that postural changes caused by those conditions induce musculoskeletal changes, and that is the cause for islet cells regeneration.  Postural changes and musculoskeletal changes are the causes for the regeneration of islet cells. How that happens I will try to explain later.

Side note: It has been nowhere mentioned, but it seems that a few examples of Weight Loss Surgery (Bariatric Surgery) performed on obese type 1 diabetics has caused a regeneration of islet cells.

 

The fact that has been known for many decades, but rarely mentioned is that when women with Type 1 diabetes become pregnant, their condition improves and some of them become insulin free during pregnancy.  But pregnancy doesn’t cure permanently type 1 diabetes because after delivery, they again become affected with type 1 diabetes.

Insulin Remissions among Pregnant Type 1 Patients has recently been highlighted by Dr Louis Jovanovic at the International Summit on Insulin Independence - April 24, 2013

 

Quote:

One third of pregnant women, including those who’ve had it for 20 years or more, have reduced insulin needs during pregnancy

Among pregnant type 1 women, there is often a decline in the need for insulin

Some women have been insulin-free throughout their pregnancy, only to return to insulin requirements after delivery.

New insulin production has been seen among type 1 patients with a history of diabetes for more than 20 years 

*Jovanovic L, et all.,Diabetologia. 2000 Oct;43(10):1329-30.

Source: International Summit on Insulin Independence - April 24, 2013 http://insulinindependence.com/insulin-independence-program.html 

 

1.    The fact that “One third of pregnant women, including those who’ve had it for 20 years or more, have reduced insulin needs during pregnancy” should be regarded as a partial remission of Type 1 Diabetes.

 

2.    The fact that “Some women are insulin-free throughout their pregnancy – can be regarded as a temporary cure for Type 1 diabetes.

 

3.    The fact that women “return to insulin requirements after delivery” – can be regarded as the reoccurrence of Type 1 diabetes.

 

The question is do women return to insulin requirements immediately after delivery, or after a few days, weeks or even months?  At this moment, I can only guess until more data is available. However, it is hard to assume that they return on insulin requirement immediately after delivery. It is more likely that they return after a period of the delivery. Also, it is hard to assume that there is some fixed timeline. It is very likely that some women return to insulin requirements in a shorter time, and some take a while longer after delivery.

 

The example of partial remission and temporary cure of Type 1 diabetes during pregnancy points out that; the musculoskeletal and biomechanical changes during pregnancy are responsible for the partial remission and cure of type 1 diabetes. The return of the pre-pregnancy biomechanics – (posture and gait) and the pre-pregnancy shape of the musculoskeletal system causes Type 1 diabetes.

 

The examples that islet cells regenerate during pregnancy further strengthens the conclusion that biomechanical and musculoskeletal changes are the reasons for the regeneration of islet cells.

Quote:

By 10 weeks of pregnancy, new endogenous levels of insulin are seen.

Johansson M at al. Endocrinology 2006. 147(5):2315 – 232

 

The fact that new insulin production starts after 10 weeks of pregnancy suggests that at that time, the regeneration of islet cells starts. New endogenous levels of insulin aren’t seen in the first or second week of pregnancy because there are almost no musculoskeletal changes. Musculoskeletal changes are visible around 10 weeks of pregnancy. 

Please note: All women during pregnancy are affected with anatomical and physiological changes. But some of them are more and some of them are less affected with musculoskeletal changes during pregnancy.

 

Halle Berry was diagnosed with Type 1 diabetes in 1989. In early November of 2007, she was four months pregnant when she stated "I've managed to wean myself off insulin.” Berry gave birth to their daughter in March 2008.

Quotes:

Actress Berry was diagnosed with type 1 diabetes at age 22, after she became ill and slipped into a weeklong coma. In 2007, however, Berry announced that she’d weaned herself off insulin. - Source: http://www.health.com/health/gallery/0,,20490828_2,00.html

Pregnant Halle Berry angers docs on diabetes - Source:  http://abclocal.go.com/ktrk/story?section=news/entertainment&id=5747206

Not only did the 41-year-old actress achieve a long desired pregnancy, but she stirred up a storm of controversy when she claimed that she had cured herself of type 1 diabetes ……

….. She claims that a healthy diet and exercise has changed the course of her illness.

Source: http://abcnews.go.com/Health/DiabetesNews/Story?id=4034836&page=11

 

I don’t see anything wrong in Halle Berry’s claim that she is cured from Type 1 diabetes, but the statement that she had done so with “a healthy diet and exercise” is not right.

 

Side note:

On the other hand, it is not to blame Halle Berry for her belief that she is cured from Type 1 diabetes due to a healthy diet and exercise. Fear from disease make us prone to believe in any explanation, it doesn’t matter how those explanation-theories have nothing to do with reality.

 

In the absence of understanding any serious health conditions, people are prone to belief.

 

In the absence of real progress in the understanding of health conditions, professional/institutional scientists are prone to invent theories and explanations that sound scientific, but without real meaning.

 

The theory that “Type 1 diabetes is an autoimmune disease” and the explanation “the immune system attacks it and destroys the cells that produce insulin” is an example of pseudo-theory and explanations that sound scientific, but have no real meaning.

 

There is no ground to doubt that Halle Berry is cured from Type 1 diabetes because a great number of women with Type 1 diabetes, after10 weeks of pregnancy, have reduced insulin needs during pregnancy (temporarily regression of Type 1) and some of them are insulin free throughout the rest of their pregnancy (temporarily cured from Type 1 diabetes).

 

Usually after delivery, or after some time after the delivery, women return to their pre-pregnancy insulin requirements, but the interesting fact is that Halle Berry didn’t return to her insulin requirements after delivery.

 

1. The first step is to regard Halle Berry Type 1 diabetes cure as unexplained.

2. The next step is to put an effort in order to discover why she has become permanently free from Type 1 diabetes.

 

Luckily, there are plenty of pictures and movies with Halle Berry while she had type 1 diabetes and after she is cured from type 1 diabetes that enables us to analyse her musculoskeletal profile, gait and posture when she has Type 1 diabetes and after she claimed to be cured from Type 1 diabetes.  More about the musculoskeletal profile of Halle Berry will be discussed later after I present some other points about Type 1 diabetes.

 

Side note:

For now there is only one example (Halle Berry) where Type 1 diabetes is cured by pregnancy. (Actually, musculoskeletal changes and the change in the biomechanics during pregnancy is the reason for the cure of Type 1 diabetes.) The question is how many other women become permanently insulin free or have permanently reduced their dependence of insulin injection after delivery. It is very likely that due to the accepted views such as; Type 1 diabetes is an autoimmune disease, diabetes type 1 cannot be cured, etc. those cases are ignored by the established scientific community.

 

Apart from the fact that in some instances like acute pancreatic injury, pancreatitis, pancreatic stones and pregnancy, islet cells do regenerate and the example of Halle Berry further suggests that Type 1 diabetes is curable.

 

One crucial fact about Type 1 diabetes, which is rarely mentioned, is the fact that the size of the pancreas of people with type 1 diabetes is significantly smaller than of people without Type 1 diabetes.

 

Quote:

Pancreatic volume is reduced by 26% in patients with type 1 diabetes within months of diagnosis, suggesting that atrophy begins years before the onset of clinical disease. Pancreatic atrophy within individuals is therefore a potential clinical marker of disease progression. Source: http://www.ncbi.nlm.nih.gov/pubmed/22879632

 

This suggests that it is unthinkable to prevent or cure Type 1 diabetes without understanding what causes the atrophy of the pancreas (shrinkage of the pancreas). (I’m afraid that putting forward a hypothesis about what causes atrophy of the pancreas and how to reverse and to prevent atrophy of the pancreas will cause confusion, and I will leave it for later.)

 

Next page: Obesity and Type 1 Diabetes – Obesity Protect against Type 1 Diabetes?

 

Previous page: Postural and Musculoskeletal Characteristics of Normal Weight People without and with T1D 
 

Modern Science of Biomechanics and Type 1 Diabetes 

 

Site Map

 

Contents – Page 1

Introduction – Page 2A and Page 2B

Postural Profile of People with Type 1 Diabetes – Page 3, Page 4 and Page 5

Postural and Musculoskeletal Characteristics of Normal Weight People without and with T1D - Page 6

Spontaneous Remission of Type 1 Diabetes – Page 7

Obesity and Type 1 Diabetes – Obesity Protect against Type 1 Diabetes? – Page 8

Weight Loss and Type 1 Diabetes – Weight loss linked to Type 1 Diabetes? - Page 9

Insulin Therapy and Weight Gain – Page 10

Exercises Induced Low Blood Sugar (Hypoglycaemia) and High Blood Sugar (Hyperglycaemia) - Page 11

 

Appendix

 

Type 1 Diabetes in American Indians and Alaska Natives - Page 12a

Type 1 Diabetes among the Amish – Page 12b

Why more and more Children are Developing Type 1 Diabetes – Page 12c

Type 1 Diabetes in Animals – Page 12d

Hypotheses about the Causes of Type 1 Diabetes in Very Young Children, Older Children and Full Grown Adults – Page 12e


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